Until ten rok ago, geneticist Don Tillman had never had a second date. Then he developed The Wife Project and met Rosie, 'the world's most incompatible woman'. Now, having survived 3,653 days marriage, Don's life-contentment graf, nedávno v jeho highest point, je curving downwards. Don and Rosie je ten-year-old son, Hudson, má školu na škole: jeho školitelia sami sa nebudú nachádzať v iných deti. Rosie je battling Judas pri práci, a don je v horúcej vode po Genetics Lecture Outrage. Pre don, learning to be a good parent as well as good partner bude potrebovať pomoc old and new. It will mean letting Hudson urobiť jeho cestu vo svete, a grappling s rôznymi truhlíky o svojej vlastnej identity. It will also mean opening a koktail bar.